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New study suggests that using Multivitamins During Pregnancy reduces the Risk of intellectual disability in Autism

A new study published in the British Medical Journal suggests there may be a link between a woman’s diet during pregnancy and childhood develomental disorders. 

According to this new study conducted by researchers from Drexel University, multivitamin use during pregnancy may protect children with autism from intellectual problems. 

“A potential link between supplement use during pregnancy and autism is intriguing because it suggests a possible avenue for risk reduction,” said Brian Lee, Ph.D., an associate professor and senior author of the study, which was published in BMJ (formerly The British Medical Journal).

Data for the study was drawn from children living in Stockholm County, Sweden, for at least four years between 2001 and 2011. Only children ranging in age from four to 15 at the end of 2011 were included.

To make results more robust, data from siblings was also taken into account to help offset some of the unseen factors in autism development, like heritability or otherwise healthy behaviors, researchers explained.

Little is known about how diet during pregnancy might affect the risk of a child developing autism, according to the study’s lead author, Elizabeth DeVilbiss, Ph.D., a recent graduate of the Dornsife School of Public Health at the university.

“There have been more studies in recent years about varied aspects of diet during pregnancy and autism risk involving multivitamins, iron, folic acid, vitamin D, and more, but the evidence is still inconclusive,” said DeVilbiss, now a postdoctoral fellow at the Eunice Kennedy Shriver National Institute of Child Health & Human Development. “More work needs to be done in this area to clarify these potential relationships.”

Hoping to clarify autism risk linked to diet during pregnancy, DeVilbiss, Lee and their team, which also included researchers from the University of Bristol and the Karolinska Institute in Sweden, also looked for potential changes in autism risk related to taking supplemental folic acid and iron. Both are supplements that have commonly been recommended for pregnant women.

While the study suggests that vitamins and supplements may be benefial during pregnancy, the exact combination of supplements for optimal impact remains unknown. For example, multivitamins had no effect on occurence of autism. 

“We cannot rule out potential contributions by iron and folic acid,” DeVilbiss said. “Diet during pregnancy is complicated, and there are important factors we can’t assess with our data, such as dietary intake, dose, and timing. This is clearly an area for future work.”

In that future work, the hope is that more specifics can be nailed down, the researchers said.

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